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Life Science U4-L3 How Cells Make More Cells

DNA: The Instructions Inside

Every cell you've ever had carries the same instructions, written in a code with only four letters. Here's how it was found, and how it works.

Teacher Notes

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Lesson Goal

Students will describe DNA as a double spiral with bases that pair A with T and G with C, explain how DNA copies itself by unzipping, and explain that a gene is a section of DNA that directs one protein, carried out to the ribosomes by RNA.

Key Concepts

The pairing rule does all the work. Because A only fits T and G only fits C, either half of a DNA molecule is enough to rebuild the other half.

A mutation is any permanent change in a gene or chromosome. Many are harmful, some aren't, and one in a sex cell is passed to every cell of the offspring.

Teaching Suggestion

Write a strand like AGTAAC and have the student write the matching strand underneath (TCATTG). Then 'unzip' it and rebuild both halves. The book's own review question does exactly this.

Key Vocabulary

DNA
The chemical in chromosomes that carries a cell's coded instructions.
Gene
A section of DNA that holds the instructions for making one protein.
RNA
A single-stranded copy of a gene that carries its code out to the ribosomes.
Mutation
Any permanent change in a gene or chromosome.
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Before You Start

The Words

The words this lesson uses. Tap a card to see what it means, then come back to them whenever a question uses one.

Part One

The Questions

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Questions about the story you just read. Pick your answer straight off, or press Find it in the story if you would rather hunt for the sentence first.

Part Two

Vocabulary Check

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The word cards are at the top of this page. Look back at them as often as you need, then answer.

When you finish: write the answers out in your own words — not copied word for word from the choices. Saying it your own way is the part that proves you understood it. Then use Print Answer Sheet for a one-page record of what was answered and scored.
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